Lena Winestone, MD uncovers effects of pre-conception smoking and racial disparities in pediatric leukemias

In a study published recently in Cancer Epidemiology, Biomarkers & Prevention, the UCSF research team showed that paternal preconception smoking decreased 5-year survival in children with AML.

The researchers evaluated whether pre- and post-natal exposures to tobacco smoke decreased 5-year survival of 1,235 childhood ALL and 188 childhood AML cases derived from a population-based case-control study in California. The patients were diagnosed between 1995 and 2015 (with a median follow-up time of 13.2 years). They analyzed data for tobacco smoking before conception, during pregnancy and after birth. The researchers also looked at parental education and income, clinical features and vital status through 2020, and also adjusted for sociodemographic characteristics and risk group (for ALL only).

To read the full article, follow the link: https://www.ucsf.edu/news/2023/12/426806/how-improve-survival-pediatric-leukemia-patients